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Gautis Fiala. More than five years after the pandemic began, questions about the origins of COVID-19 remain hotly debated. In our episode today, we speak to a physician scientist and author of the new book The Code As Witness. He argues that the strongest evidence for the lab leak theory comes from the genetic code of the virus itself.
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turns and conditions may apply. Joining us now to discuss the clues, pointing to a lab origin found in the virus itself is Dr. Stephen Quay. Dr. Quay, thanks for coming on. Well, it's a pleasure to be here, Georgia.
So, Dr. Quay, it's been five years since the pandemic began, and most people have moved on. But you've actually written an entire book that questions COVID origins and talks about why that still matters. Why did you choose that as the topic of your book?
Well, I mean, I was looking at what was going on in 2020, and seeing two things happening at the same time. One was a representation of where the virus came from that didn't make sense scientifically. And then in a parallel fashion,
the science establishment was really censoring. People who had opinions, there wasn't the opportunity to debate, which is the foundation of science. So, both of those drove me the right to book.
And the third thing is that there may be another pandemic,
it could be worse than the 1% SARS-CoV-2. We need to be better prepared, and we're not. Now, you've argued that the virus itself contains some clues that point to a lab origin. What is the strongest piece of evidence that you've seen
“that makes you feel like this virus came from a lab league?”
Well, it's looking at the virus and comparing it to thousands and thousands of viruses we have from nature. So, it has a particular cycle, the fur and sight, which makes it highly transmissible, not found in nature in this class of viruses.
It has some unusual adaptations to the human tissue that are not seen in viruses in nature, because in nature viruses are living in animals, you know, bats, and other kinds of intermediate hosts. This virus was highly adapted for humans from the beginning.
It's also the first respiratory virus that was ever transmitted asymptomatically. And I show that for five years, the one in psychology was studying how to make a virus that could transmit without getting symptoms.
Those are the three primary foundations inside the genome that say that it came from a laboratory, and was manipulated in that laboratory. When you say that it could be transmitted without symptoms, you mean in that pro-drome phase
before the symptoms arrive? So, a new virus coming from nature is going to cause symptoms in 98, 99% of patients. The symptoms are fever, sweating, red cheeks, and the like, because it runs into what's called the innate immune system,
because it's not used to, you know, to be immune humans. This virus was 40 to 50% asymptomatic in its patients.
We missed that for a few months, because we never expected it to be asymptomatic.
That was one of the two or three things that contributed
most to making it a pandemic, a worldwide condition,
where, you know, it has infected probably every person on the planet. And you say there was evidence that they were working on making something exactly like that in the lab? Yes, there's a particular gene called an accessory gene. It has the fancy name of Orphate.
I'm being facetious there, but Orphate is responsible for suppressing immune system, so that the body doesn't react to it. On the front end of an infection, it makes it an asymptomatic, and on the back end, it makes it hard to make antibodies against the virus. We've seen this virus, you know, affect people over and over again.
And part of that is this protein called Orphate,
that's actually suppressing the immune system at the end of an infection. Now, the title of your book that you often use, and it's a phrase in your book, is the code as witness. Can you just unpack that phrase a little bit?
“And what aspects of the virus are you referring to there?”
And it might be the aspects that you just discussed. Yeah, I mean, the title is to indicate that there's been a lot of what I would all call. He said she said evidence around where the virus came from. So we have, we have Verologist talking about that. It came from a market publicly.
And then through FOIA and other means gotten access to their private statements, where they say, guys, this could really have been engineered in a laboratory. I don't use that evidence. I use the evidence inside the virus itself, because that's, you know, apolitical, and really is the best place to find the evidence.
This virus has features that have never been seen in thousands and thousands of viruses from nature.
And those features are specifically the kind that have been used over the last 20 years to make viruses more effective in the laboratory. So it's circumstantial evidence, but much like fingerprints are circumstantial evidence. This points to a lab origin and a manipulation of the virus in the lab.
“Now, how large are these gene sequences that you're referring to could?”
Some people say, oh, they just arose spontaneously, or just mathematically, does that not make sense based on how large they are? Well, they are different sizes, so the fear and cleavage site, the thing that makes it so transmissible, is a 12 specific new letters in the virus that have never been seen in a thousand years in viruses from this class.
The adaptation to humans is up to 100 different sites on the spike protein that are ideal for the human receptor, but not for the bat receptor, not for other post receptors. If it came from bats, would you see some evidence in its genome of where it historically would have favored watching on to bats? Well, yeah, so the exact, what you're describing are two exact incidents.
So this is a coronavirus, and in 2014 we had a coronavirus epidemic. In 2003 we had a coronavirus epidemic. Both of those came directly from animals to humans. In one case, something called a civic cat in markets in China and the other from camels to humans in the Middle East, and those viruses had the hallmarks of having been in
“respectively, civic cats and camels, and so that kind of evidence is what you should see in a natural”
spillover, which are completely absent in SARS-CoV-2. Well, that brings me to the next question, because some people who disagree with you say the evidence does favor that natural spillover, can you just explain a little bit what that term spillover means, and then your response to that critique? Yeah, so let's back up a little and do a little biology training here.
A zoo analysis has the word "zu" in it. It involves three entities, a human, an animal, and a virus, or perhaps a bacteria. If you hear about a new spillover in China, for example, in Asia, it is eight to one likely that it's a natural event coming from nature versus a laboratory event, because that's the incidents that happen in Asia, and that's why I build the case that it's beyond a reasonable doubt
that this came from a laboratory. Every year, there are on average eight natural spillovers from nature to humans that end up in the hospital, or you know, in a clinic that we can detect. And in that same time, every year, there's one, approximately one lab incident where some in a laboratory gets infected, they go out into the world, they begin to infect other people. So it's eight to one in favor of nature, and that's your starting point, and that's a starting
point in the book. But with the evidence, I'd actually flip so that it's greater than 95% likely it came from a laboratory. The flip side is to be sure everyone understands that that there are thousands of laboratory accidents around the world, you know, in the last decade, for example, where people, people actually died from laboratory experiments they were
Conducting.
of laboratories doing this kind of work, and the pervasiveness of the microbes themselves.
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“issue or do you think it was institutional, like the guard dog institutions failed at their position?”
Yeah. That's a complicated question. The two features of the virus that were unexpected for the
frontline doctors and had they known they would have acted differently and had they acted differently,
we would not have probably had a pandemic. Is the rapid human to human spread and the fact that about half the infections are asymptomatic. I spoke before about eight natural zoonosis per year in Asia for example. When they happen, one person gets sick and maybe gets very sick and maybe even dies, but because the pathogen, the virus is not adapted to humans, it doesn't go beyond there. Maybe very seldom, in fact, another person at all. So the frontline doctors when this
came out were expecting a virus that yes was going to be dangerous for the people who had it, but wasn't that transmissible? And having the fact that it clearly shows that 99% of its recognition site for the human ACE2 were preadapted, made it a highly human to human pathogen from the beginning. And then the other thing is again, only 1% of viruses from nature are asymptomatic. And so none of our people expected that there was asymptomatic transmission, which would have
changed how we treated, you know, airports surveillance or shutting down travel on those kind of things. Yeah, now is the gain of function research still happening? And if so, how should it be governed
“and how should it be managed? Yeah, I mean, I think it's still as occurring. It's defined as”
is changing the properties of the pathogen and the human pathogen, making it more infective. So it takes a smaller amount, making more pathogenic or likely to kill you and the like. And it is going on now. And as part of the provisions that I suggest in the book is putting all of that under an independent, you know, national surveillance group, a research study group that would look at this research and whether it's expected to cause benefit or it's just too risky to do. Right now,
the people who are funding the research and doing the research are part of the people who decide whether the grants are appropriate or not. And that's there's too much self-interest in that current cycle. Now, it's possible that a lot of the information was either hidden or destroyed. But if you, or we were somehow able to gain access to 100% of the lab data, all of the correspondence emails, internal records, etc. What do you think we would learn that still hasn't been exposed
“today? Well, I mean, I think the, the chain of custody on a natural virus that gets manipulated”
in a lab in two or three ways, including, you know, if you're in a cleavage site, including a adaption to the ACE2, I think that if you had the laboratory notebook, you would see the steady progress, probably takes six to 12 months to do those activities. So you'd see the steps along the way that led to all of that work. And that would probably blow the lid off of where this specific virus came from. Well, I think, you know, I've done an analysis because to remind, you know,
your, your viewers, the techniques for manipulating coronaviruses were developed at the University of Carolina by, by a scientist called the Ralph Barrick. And, you know, it really is very inventive and creative fundamental research that he did in terms of making consensus viruses. So growing viruses, including crow before, be able to do reverse genetics in the laboratory. So you can manipulate
Them and make large quantities of them and do extremist transmission so you c...
the detection of the act of the work itself. He called it the no CM technology where you,
“you can't actually detect viruses being done. So all of the work was done in North America,”
but when you publish it, it becomes available to everyone in the world. My analysis was given the
location of the initial cases and the early spread and then the proximity of the, of the,
“of the cases in China, uh, in Wuhan itself. Uh, that is the 70, 30 or 80, 20 likely location”
of the laboratory that did the work. Who on Institute of Rology in Wuhan, China.
All right. Well, Dr. Quay, thank you so much for coming on and explaining all of this to us.
“Thank you, Georgian. That was physician, scientist, and author, Dr. Stephen Quay. And this is”
been a week in the dish in the morning one. Hold it in your mouth to go. Tiefen and Span with Viso Steuere.


