Most Replayed Moment: Mouthwash REVERSES The Benefits Of Exercise! Dr Nathan Bryan

Well, I think the most important thing we've earned is what you shouldn't be doing.

So it's not what should we do, it's what we shouldn't be doing, number one, we have to get rid of fluoride. Just this past weekend, I was speaking at a dental conference in Salt Lake City and there were there people there from the National Toxicology Program, which in the U.S. is the organization task with if there's any kind of risk of exposure of a environmental toxicant, they're charged

“with doing the toxicology studies to see if there's an increased risk, what is the risk?”

And is there a safe level that is without risk? And what they report is the fluoride, there's no benefit of fluoride and it's all risk. It lowers IQ and kids by as much as seven points. And it shuts down your thyroid function and it's a neurotoxin. And as I mentioned before, most toothpaste has fluoride in it.

And if you read the back of your toothpaste, it will tell you, at least in the U.S., I don't know about in other countries, but it says, if you swallow this, call poison control because it's a poison. They're putting poison in toothpaste. And then if you also pay attention, it says, only put a pea size amount of toothpaste

on your toothbrush, a pea size. But everybody that I know fills the entire bristle of the toothpaste with toothpaste with toothpaste. So that's about 10 or 15, sometimes 20 pea size amounts of toothpaste. And a pea size amount of toothpaste contains about half a milligrams of fluoride.

Now if you're using 10, 20 times more than that pea size, now you're exposed to five milligrams, 10 milligrams of fluoride. And you don't even have to swallow it. This is a very small molecule, I'm like it a week of 19. So it's absorbed directly across the Pico-Macosa, the oral cavity, and it becomes systemic.

Have a more diverse oral microbiome, and they seem to have better oral health. Why is this?

My girlfriend's been banging on to me, she's always bloody right.

My girlfriend's been banging on to me about tongue scraping for the last two years. And I've kind of just ignored her, I'm just kind of, yeah babe, sure. When she's not in the bathroom, bathroom, I'm not using her tongue scraper because it just looks strange and I, for me, based on what I knew about the oral microbiome in the

“microbiome, generally, I'm like, should I be scraping off all my bacteria?”

Well, if you're going to plant a garden, do you plant a garden on until the soil? Yes and I don't know anything about gardening, that's going to run the garden, so maybe yeah. Well, I grew my own food. Okay.

So you have to tell the soil, right? You got to break up the soil so the seeds actually can be aerated, and you just break up that biofilm. Yeah, you take the back of the dorsal tongue, I mean, almost to the point of the gag reflex, and you just pull that ideally copper tongue scraper forward, and you're going to see this

group coming in there, but it's like kind of like telling the soil and it's increasing the diversity of the dorsal part of the tongue, the microbiome. So my girlfriend was right. In that regard, yes, but what we found was in that one kid, we saw the greatest increase in blood pressure, if you tongue scraper and use an aceptic mouthwash, that's the absolute

worst scenario. Interesting. If you think about this, you're tongue scraping, you're opening up the pores, and now you're using mouthwash, it's better to get easily penetrate deep in the grips of the tongue, and more effectively kill the bacteria.

So you want a tongue scraper and then use a toothbrush without fluoride toothpaste. Absolutely, and no anaesthetic mouthwreens. Okay. And what about going to dental hygienists and things like that? Do you think that's a advisable idea?

Because once every culture or so, I'll go and see a dental hygienist just to get everything sort of clean down.

“I think that's a good proactive practice, but because you need to look at the health”

of the gum tissue, and the gingival tissue, and a routine clean and scraping the plaque off the teeth, and allow it to make sure you have good mineralization of the anamol of

the tooth is good, but never let them do a fluoride rinse.

Okay.

chicoxide that I need to be aware of before we move on?

Yeah, there's also data showing that if you use mouthwash, you lose the cardiovascular benefits of exercise. So think about this. We know that diet and exercise is the best medicine, and many people aspire to do that. They go, and they try to eat good, they avoid the temptations of sugars and sweets.

The exercise every day to try to increase their longevity and cardiovascular health. If you do that in your using mouthwash, you no longer get the benefits from exercise. And we've already established, you don't get the nitric oxide benefits from diet. So two out of three Americans wake up every morning using mouthwash, and two out of three Americans have an unsyphalivation and blood pressure.

What's the mechanism now?

Well, because you're killing the oral microbiome that's partly responsible for production

of nitric oxide and nitric oxide, you get constriction of blood vessels, and it leads to high blood pressure. That's crazy. And is there a link between our hormone levels, things like my testosterone levels, and the nitric oxide?

Yes, so this is a two-way street, so in men testosterone activates nitric oxide production. Okay. In women, estrogen activates and stimulates nitric oxide production. Okay. So as long as we have optimal sex hormones, and as long as the enzyme in the lying in the

blood vessel can functionally produce nitric oxide, that explains the cardiovascular

benefits of hormone replacement therapy.

So taking testosterone or estrogen therapies helps to increase my nitric oxide levels. As long as the enzyme is functional and coupled, which means that we have to understand the insamology and about chemistry of that reaction to where when it's exposed to testosterone, the cell can actually make nitric oxide in response. And there's a two-way relationship as well with exercise then, because I've read in your book

that exercise activates and stimulates nitric oxide production, but you also just told me that

“if you want to get the great benefits of exercise, you need nitric oxide in the first place,”

because else your blood cells are going to be very narrow, less oxygen-traveling-three, but you're going to do a worse workout as well, presumably. Well, thank you. I mean, there's other magnets too, like vitamin D. I mean, most American-judicision vitamin D. People with low testosterone have erectile dysfunction, and why is that because they're

not stimulating nitric oxide production, and they're not dilating the blood vessel so they develop ED? So all of this no matter what it is, with related to vitamin D deficiency, which is activated or stimulating nitric oxide, if it's low hormones, if it's poor diet, sedentary lifestyle, all of that can be explained by insufficient nitric oxide production.

Well, I want to think about the rule that food plays in my nitric oxide production. That should I be eating to increase nitric oxide levels, so to keep them at a healthy level. I think the same answer is for that too. It's not so much what we should be eating, it's what we should not be eating. Okay.

So we'll cover this step by step. Number one, you have to avoid sugar, and high glycemic index foods, because sugar is a toxin, it's a poison, and I think about what sugar is. So when we eat sugar or drink sugar beverages, whether it's sucrose, whether it's fructose, whether it's high fructose cornstrip, the end result inside the human is we see an increase

in glucose. So elevation in blood sugar or blood glucose is diabetes, right? And now there's continuous glucose monitors that you can get anywhere, and everybody does this. So if you eat something, and it causes an increase in your blood sugar, blood glucose, then

“you should avoid that, because glucose is the name applies as glue, right?”

It's sticky, and if you have a soda, and you spill it on your countertop, you come back the next day, it's sticky, that's what happens inside the body. That sugar sticks to everything, it sticks to proteins, it sticks to enzymes, it binds to hemoglobin, and sugar stuck to hemoglobin is what we call hemoglobin A1C. And what is that?

It's a marker of long term glucose control, if you have a blebicaly, when you want to see it's greater than 5.7, you're diabetic. So it's not just hemoglobin, it sticks to the enzyme that makes nitric oxide, and in biochemistry and in zymology, enzymes have to be able to undergo conformational changes, right? So it transfers electrons from one donor to an acceptor, and that's how biochemistry is done.

But if sugar is stuck to that enzyme, it locks it in some confirmation and it can't do its job, for instance, it can't make nitric oxide. So sugar is an absolutely poison, and it kills many enzymes and binds to everything. And it lowers nitric oxide production?

“Absolutely, that's why diabetics have a 10-time higher incidence of heart attack, stroke,”

all cause mortality, mortality.

That's why they have non-healing wounds.

There's no nitric oxide.

“That's why they're developing diabetic retinopathy, macrotic generation, pancreatitis.”

I mean, all of that can be traced back to a lack of nitric oxide production, because the sugar stuck to the enzyme, the sugar destroys the oral microbiome, and completely changes the ecology of the bacteria, and completely shuts down nitric oxide production. Just a bit of a tangent now. You mentioned that's why they have open wounds that directly.

Diabetic ulcers. OK, so nitric oxide's playing a wrong healing role in wounds. Absolutely. So I've got this guy on my head. I was playing football the other day.

Someone ran into the back of my head, and they passed out, and got taken away by an ambulance. But I was just left for this big scar on the back of my head, which I've had like glue stitched. Yeah. I'm wondering, I'm like, if I apply the nitric oxide serum, it'll stimulate blood flow

to that.

It'll improve cellular turnover and heal that wound and basically remediate the scar.

And how do I do that? Is it? Yeah, you see, take one pump from each side. So one pump from this side. We'll turn it around, one pump from the other.

Yeah. And now, if you apply that and mix it together, as soon as you mix it together, it starts to generate nitric oxide gas. So then that gas will diffuse into that tissue. It's going to increase blood flow, and it's going to mobilize stem cells, and it's going

to improve cellular turnover and completely remodel that and heal that. And if it were an infection in there, it would kill the infectious bacteria. OK, well, we shall. Second of course. We shall see if that works.

So back on this point of view, then, so Sugar's Bad. Sugar's Bad. Yeah, you got to eliminate sugar. And I think the benefits of it like a straight ketogenic diet or a straight vegan vegetarian diet is just the elimination of sugar and carbs, right?

“But I think, to answer your question, what should we be eating?”

I think you've got to eat a balanced diet in moderation. You know, Americans are overfed. How you got to do is walk around and see the epidemic of obesity. Good high quality protein, good quality fats, and little or no carbs. And it's really that simple.

And why did you write a book about Beatrice? Beatrice? Yeah, the beats hit the, really, the airways back in 2012 in the London Olympic Games. There was a lot of data coming out at the time of the benefits of beetroot juice on enhancing athletic performance.

And there was a benefit of the nitric oxide being produced that could explain the improvement in athletic performance.

The problem is these athletes were drinking liters and liters of beetroot juice and causing

a lot of gastric discomfort, causing diarrhea. Their urine and the feces would turn red and a lot of people interpreted misinterpreted that as gastric bleeds or urinary bleeds. And then when I started looking at the products on the market, most of the beat products, the desiccated beat powders provided zero nitric oxide benefit.

They didn't contain any nitrate, no nitrite, they were just, we call them dead beats. They're dead beat product. And so I thought if people, if consumers are out there looking for beats because they've been shown to enhance their performance, but that enhancement in performance was dependent upon the beats ability to improve nitric oxide production in the body, then the non-scientist

outfit, you wouldn't know what to look for, right? They're buying products that aren't providing any benefit to them. And so years ago, we would do randomized placebo-controlled clinical trials and we would take some of these commercial beat products that you can go to your local nutrition store or pharmacy buy off the shelf and we would use those as placebo and our clinical trials because

it's the perfect placebo. So what I tried to do in that look is educate, okay, what is it about beats that are so

“important, what's the mechanism and what is necessary in those beats that can improve nitric”

oxide production. So again, everything I do is intended to educate and inform the consumer so that they know how to make informed, educated choices on the products they're taking or the foods that are eating or their oral hygienic practices. I'm trying to find the page in your book, but there was a page in your book where you describe

beat treat as the most underappreciated food in the history of eating. Yeah, that may be in the beat the odds, but if you go back to historical times and you look at the how we're going to fix some caves of the ancient cavemen, you know, people thought they were drinking wine because they would have these red stuff in this before battle. But what these ancient Egyptians were doing was they were drinking beet juice to improve their

performance before they went into battle so that they were ready. They were energized and improved their circulation. So that's the historical study on beats. And obviously, these were beats grown at a time when there were no herbicides pesticides

So these beats were full of nutrients, probably full of nitrate that provided the benefits

of that. Unfortunately, today the beats that are grown at least in America really are nutrient depleted just like most of the food. So would you recommend people eat beet treats? No, because as we again, through our survey that we published in 2015, we realized that you

really can't eat enough beats to get enough nitrate to improve your performance. And the other caveat is that if you're using mouthwash, you've got fluoride in your toothpaste or fluoride in your drinking water that you're mixing the beat pattern in, you're not going to get a nitric oxide benefit from it. There's a graph in front of me here, which I printed off, which shows the rise in antacid

medications.

Oh, yeah, from 2004 to so a 20 year period we're seeing, what is it, almost a quadrupling

“of the use of an acids and this is globally or is this in the U.S.?”

That's worldwide, I believe. Yeah, worldwide. Now, this is a problem. I mean, these, these antacids, what is an antacid? So it's a medication that's given only to suppress stomach acid production.

And as a biochemist and physiologist, I can't think of nothing more damaging than to inhibit stomach acid production, because stomach acid is required to break down proteins into amino acids, whether it's you eating animal protein or plant-based protein, it's required for nutrient absorption. You need stomach acid to absorb B vitamins, you need stomach acid to absorb selenium, chromium,

iodine, magnesium, iron, I mean, most nutrients, micronutrients are absorbed in the

lumen of the stomach. And if the stomach can't, is not making stomach acid, then these nutrients are not absorbed. And most Americans, 75% of Americans are deficient in magnesium. And any 75% of Americans are deficient in iodine, I mean, it's a huge problem. These are the browns like Gaviscom.

Now, these are like the pralusic, the prevacids, the nexium, the prescription medications

“are all mepresol, pentopresol, today in the U.S., I think it's probably worldwide.”

You don't even need a prescription for these from your physician. You can go to your local drugstore and you can buy these, what we call proton pump inhibitors from PPI's, we're about tombs over the current. So there's a difference in, so tombs and things like baking soda are a buffer, right, sodium by carb or calcium carbonate, and it's a buffer, right.

So if you, if you have an acute, about a hypersacretion of acid, you can take a tombs or some buffer, some base, huckle and substance to neutralize the acid. Realizing acid is completely different than inhibiting its natural production in the polaric cells of the stomach. So what is the difference between, have you heard of Gaviscom before?

Yes. Yeah. What's the difference between, are you like a Gaviscom? Well, there's certain classes of an acids, there's what we call h2 blockers, there's proton pump inhibitors, and then there's the natural buffers that are just neutralizing the acid

environment in the stomach. Gaviscom, I'm trying to think what class that falls under, I don't think it's widely used here in the U.S. I mean, the main drugs used here are probabilistic nexium, preversed, those are the over the counter, and then the main prescription medications are the homepersal and the pentopersal.

Gaviscom is a commonly used antacid brand, and the active ingredients are aluminum-hyde drugside and magnesium-car carbonate. Oh, so we have this kind of number one, it's got aluminum in it, which should absolutely be avoided. But yeah, it looks like a buffer, it's got an hydroxide aluminum-hyde drug side, which

is a strong base, so it's neutralizing the stomach acid production.

“But it's a neutralizing agent, but anything that contains aluminum, you should absolutely”

avoid. I mentioned a few times today, but my girlfriend's a breath practitioner, she runs a business called barley-breathwork.com/agad, and one of the things she's talked to me a lot about is mouth breathing, and I know there's a relationship between nitric oxide and how we choose to breathe whether it's a raw nose or a raw mouth, can you explain to me that link?

When we talk about the enzyme that's found in the lining of the blood vessels, we sort of this segment. That same enzyme is found in our epithelocyls, in our upper airways, in our sinuses. So just like exercise can activate nitric oxide production in the lining of the blood vessels, deep breathing, nasal breathing activates that enzyme in the epithelial cells of our sinuses.

And so when we do nasal breathing, it's activating the enzyme to make nitric oxide, and now we're delivering that nitric oxide gas into the, the brachios, the lower airway. It's dilating those brachios, moreover, it's dilating the pulmonary arteries. So now we're improving oxygen uptake, oxygen delivery, and that's why nasal breathing and deep breathing has been shown to lower blood pressure.

This is a pretty crazy graph I took from Google as well, which shows just how interested

Oh yeah, again, going over the past 20 years.

“Yeah, no, I think there's a lot of people, I mean, obviously you're girlfriend, there's”

a Patrick MacKoen, MacKoen in the, I mean, the UK, it's Drugonsten, I did it made them an offer in Drugonsten. Yeah. Yeah. No, I think the benefits of that are pretty well and mechanistically we understand the benefits

of it. So the mouth breathers are not only bypassing this nitric oxide production pathway, but when you mouth breathe, it completely changes the microbiome. So you're not only bypassing the nitric oxide producing in the upper airway, but you're inhibiting nitric oxide production in the mouth from the microbiome, because you're fully

oxidating the mouth, it's changing the pH of the saliva and completely changes the microbiome

and completely shuts down nitric oxide production. Interesting. Interesting.

“So you have to, I mean, I'm a big fan of the mouth taping, but for me, I'd know, and”

I watch my kids. But sometimes there's anatomical issues where there's obstructive airways and airway obstructs and that has to be corrected by dental appliances or sometimes surgery. But the worst thing you can do is tape your mouth in your airway be constricted and, you know, you suffocate, so before you do mouth taping, you need to get some some imaging done from

your dentist to make sure that your airways is open to where if you force to breathe through your nose, you can actually have oxygen exchange.

And is there anything else that I could and should be doing to increase and improve my nitric

oxide levels that we haven't talked about yet? Humming, you know, there are certain frequencies with done this and looking at nitric oxide coming out of the ex-held breath when you're humming. So certain frequencies can activate this enzyme and it's dependent upon the volume of the nasal sinuses.

So there's not one frequency that would work in every single person, because the volume of your airways and oral cavity and sinuses would just probably much different than mine. Give me an example, show me. Well, if you just, you know, like, homes like we do in meditation or just simple humming, you could actually, so if I had my ozone gas phase analyzer here, I could humm, and I could

detect nitric oxide coming out of my ex-held breath. Because of the frequency of the frequency and activating the nitric oxide synthase enzyme. But if you take older patients, and we've demonstrated this, it's published years and other groups have demonstrated this, older patients that their enzyme isn't making nitric oxide, whether they do nasal breathing or whether they do humming, there's no nitric oxide

coming out. So again, this is an activator and a stimulator, but it's dependent upon the function of the enzyme that makes nitric oxide. If your enzyme is broken, humming nasal breathing exercise isn't going to produce any nitric oxide.

Is there anything else that I should be aware of if I'm trying to improve my nitric oxide levels? I think it's, it's, it's doing the things that disrupt it, get rid of fluoride, get rid of mouthwine, stop using an acid, stop eating sugar, anything that leads to an elevation in blood sugar, a balanced diet and moderation, moderate physical exercise, 20, 30 minutes

of sunlight a day. Sunlight. Sunlight. It both ends of the visible spectrum, both are the UV spectrum and the full spectrum infrared. So those frequencies and vibrations, again, stimulate nitric oxide release.

So the UV has an F energy to riddle, it'll not nitric oxide bound to a cystine thio on protein and then the UV spectrum will release nitric oxide down the metals. So you mean go out in the sunshine, but also those red light beds instead? Yeah, the red light have an infrared, red light bed, I have an infrared sauna that uses red lights and it needs, I use it every day.

Cool, nitric oxide production. Yeah. And there's, there's not the benefits of light, you know, it can stimulate mitochondrial biogenesis and improves energy production, it can lower blood pressure, but it also benefits of light there to be.

And yet, we're programmed to not go outside, if we go outside, put on SPF 60 and touch the cater, serve with these cancer causing chemicals and sunscreen, I mean, thanks no sense. What you just listened to was a most replayed moment from a previous episode.

“If you want to listen to that full episode, I've linked it down below, check the description.”

Thank you.