The Dylan Gemelli Podcast
The Dylan Gemelli Podcast

Episode #109: The effects of GLP Drugs on Aging! Are GLP drugs accelerating aging?

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Episode #109:  The effects of GLP Drugs on Aging!  In this episode I take a deep dive into a concept that most do not talk about or think about.  Could GLP drugs be accelerating aging?  As more data c...

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With over 20 years in the supplement industry, I have seen and heard it all. Empty promises tricky marketing,

raceded money, leaving so much left to be desired

and creating feelings of resentment. Thankfully, I'm positive by nature

and stay on the lookout for the next breakthrough product

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Use my code Dylan for an extra 10% off and start to treat your mind and body today with Tonum. Are your GLP1 drugs actually accelerating aging? Are we missing the bigger picture here when we're looking at side effects and benefits

when it comes to GLP1s? Why is it that the focus is strictly in one area and we're not looking at other areas? Or is it because people don't want us to know? Why hasn't this been talking about?

Well, I'm going to do what I always do

and that is dig deep into anything that's polarizing or confusing or being ignored. I am Dylan Jimelli, I am your resident biohacking expert whatever you wanna call me and I learn from some of the greatest minds all over the world

and so, within my first for knowledge and truth, I have discovered some new things here.

And that's why I wanna talk to everybody specifically today

about the effects of GLP1 drugs on aging. Now, this really takes us to understand the redox biology and basic biochemistry. Our bodies run on what we call any electron below. So, when we're looking at this,

we have to understand that health is the maintenance of proper reduction oxidation balance. So, when that balance collapses, what happens? Aging acceleration. So, to make this a little bit broken down,

both GLP1 manipulation and chronic immune stimulation increase reactive oxygen species, how through iron oxidation. So, what happens is, is that iron while it's in an oxidized state becomes a catalyst

for radical formation. So, those radicals damage proteins, lipids, and mitochondrial membranes. So, then what happens?

Well, the consequences actually show up downstream.

Bone loss, muscle loss, hormone decline, immune dysfunction, why does this happen? Well, because iron-driven oxidative stress actually interferes with mineral balance and also mitochondrial function.

So, calcium is extremely critical

to mitochondrial enzymes and the rotational activity of ATP synthase. So, then what happens? Well, lower calcium availability slows enzymatic spin rate. What that? Well, the lower the spin rate,

the less ATP production that we actually have. So, when we have that lower ATP, it actually tells our body to then downshift metabolism, how through reduced thyroid signaling. Then what happens?

Well, we have a result here that's not great. Slower metabolism, declining tissue repair and and accelerated aging. You can see it with people that use GLP's long term. What am I seeing?

What have I been actually shown? It's been put in front of me. Loss a muscle, like I said, loss of bone density, declining sex hormones, increased infections, and also, unfortunately,

arterial plaque, protein-miss folding. So, when you see those plaques and protein aggregates, they resemble the same pathological structures that we see in, unfortunately, Alzheimer's disease and a thorough sclerosis.

Modern culture doesn't want to accept this, because we're all care about how we look instead of the science and the biology

That's right in front of our face.

I see this happen all the time.

We hear what we want to hear. We don't do anything but justify what we want to happen.

And we gloss over and overlook the things

that are actually right in front of our face. There's multiple reasons for that. I'm not going to get into the science behind what we think, because everybody has their own desires and wants. But most of the time, we all have done this at certain points.

We tell ourselves what we want to hear and oftentimes what we need to hear goes to the wayside. And that goes without saying, "We all do it. I've done it for so many years." It doesn't matter what it costs.

I went through this for years and years and years with coaching bodybuilders that we're using animal exterior. They only live for today and they only care or worry.

It all falls into the vanity realm. Now for bodybuilders, it's maybe for their competing, but we all go through this vanity phase sometimes people forever.

Where how we look what people think, what's seen on the surface,

shapes how we feel in our everyday life.

And it's unfortunate. I was a former model. I've had an eating disorder. Nobody knows this better than me. And I've all the people that I've coached

and I've observed all of the different neuroscientists that I've spoken with and interviewed partnered with on work psychologists that I've talked to about this for my own personal and then understanding the thinking and thoughts of others

because I've taken so much time into trying to learn about why people think what they do. And we don't think about in the moment doing these things. What is this costing us? How was this affecting our long-term life?

Is it taking years off of our life? How was it affecting our loved one? It's so difficult. We have a temple, which is our bodies. If you read the Bible and you read scripture,

our minds and our bodies are intertwined and connected. And when they're out of alignment, we have nothing but problems. And a lot of the desires and thoughts that we have create a full-blown problem.

And it takes years off of our lives. And I'm saying this because that correlates to the use of some of the drugs that have been put out in front of us that we don't really understand how they fully work.

We don't understand the long-term ramifications. We don't understand the years that they're going to take off of our life. I want to explain something here. We see the science behind everything that I'm discussing,

but I want to get into a more personal, structured discussion on this. I want people to get a full-blown understanding on a personal level of what I've observed and what I've seen over all the years

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So use my link in the description and code Dylan to say 15% off today. Some of the people that I respect the most that have taught me the most, stand by what many GLP ones and other drugs can do.

And I don't disagree. They're just misused. They're misguided. People don't understand. We're looking at people that we worship

like idols because they're famous. And they say they use it or do it. And nobody will ever discuss the problems that go along with it. Everybody glorifies everything.

You can't look at someone's Instagram and think that that's reality all the time. People don't take you behind the scenes of what their life is really like. And we get so caught up in how we appear and look to other people

that we forget what's most important.

We forget how to understand and interpret what we're doing to our bodies. There's a lot of benefit to GLP one

Drugs in microdosing used appropriately for people

that it's okay with their bodies and what their family

histories are. And these aren't meant to be used forever.

And these, you have to ask yourself this.

Now I know I talk about God all the time. And if you don't fall in line with that, then just look at it from the science side. Does this seem natural that we shut off our brains to tell us that we're hungry

so that we don't eat? Even if you are not a God-fearing individual or appreciate the structure in which he designed our bodies and you just look at it from strictly science. Just look at everything in that way.

Do you think that it's smart to change the way our body runs? Does that sound like it's something that's sustainable and healthy to alter one of the main structures of how we live? No, it's not.

That's not what GLP ones were even created to do.

That's a secondary mechanism of action

that they've found when it's a diabetic drug to start with. So don't you think that by doing these things that go against the structures of our bodies that there's gonna be some negative ramification? I'm not saying that they're terrible.

I'm not saying don't use them. That's not what I'm saying and I'm certainly not trying to instill fear but what I am doing is bringing up the truth and the honest things that people like to overlook

and talk about something that nobody really talks about when it comes to the aging. And you think about this when I talked about immune function, I talked about people becoming more sick, having more trouble dealing with illnesses

and their body fighting these off. I mean, when you're out of reduction, oxidation balance and the problems that that has, we need to discuss redox more, the whole biology behind it which I will do.

But when you're disrupting mitochondrial function,

when you're disrupting mineral balance, when your minerals are out of whack your heart rhythm soft, you're gonna be cramped, you're gonna have all sorts

of problems that mitochondria are the key to our existence

essentially. I mean, all our energy is produced in our mitochondria which are the powerhouse of ourselves which the cells make up our entire body. There's millions and trillions of cells

within this body and this structure. And you think about that. And you're causing disruption there in a major way. Of course, that's going to affect our aging process.

Of course it is. So think about this. Are there ways to lose weight? Which may not happen so easily, may not happen overnight,

but that are healthy, that are the right ways to do it, are there ways to lose weight that are safe, that are effective if you just have some discipline, if you just work at it, if you just work on your diet,

if you go work out a little bit, if you prioritize everything in your life that is going to help you balance out your health with your mind and your body. Can you do it?

And can you live a long, healthy life by doing it? Or do you wanna take a shortcut? Be abusive with it. Only worry about how you look without an understanding of the long term effects.

And in all honesty, ask yourself this when you look in the mirror, when you see people with sagging faces and bone loss and degradation and injuries and muscle loss, does that look good because the scales later?

Because honestly, when you look at the people

after they've used it and you see people talk about oh, "Sempic Face" and this and that, does that look good? So if the whole goal is something vain and vanity and the ultimate outcome is bad.

Well, I like to do this risk versus reward when I'm weighing out my option. I don't see the reward being worth the risk. And I don't know how great the reward even is when you look at it on the surface.

How great is the reward? If you end up kind of looking like shit and you don't feel good and you don't like what you see in the mirror and you got long term damage. How good is the reward?

Do you want to age quicker because you wanted to lose some weight and mind you? Most people that lose weight too fast. It makes them look a hell of a lot older. I'm not saying you want to walk around with a really bloated

and heavier face. That's certainly not the case. But when I've lost too much weight too fast, I go back and look at the videos that I looked terrible and I say to myself, "Well, I thought the scale looked great

but I don't look so great." And people notice and you don't feel great. Think about this too and you lose too much weight too fast about the brain fog, the lack of energy. Everything just goes down, your attitude, your response to things.

It's just not there, your more short tempered. You don't get along with this people. You're certainly not as successful. These all happen over time. And let me tell you something.

Sarco-pini is a very real thing. And when you look at the muscle loss that people

This is all in studies on percentages,

I'm not making this up.

I mean, you can go look for yourself and listen.

I've tried, I have now had thousands of clients over the years

that have used these. I care about real world and real life experiences and observations. And I have seen it all. And I know what happens and goes along with this. And I can tell you this.

I have seen far more bad outcomes than good ones. Like I said, there's a purpose to these and they serve a purpose, but it's just like anything else.

You can drink too much water and kill yourself.

When you misuse things, you create nothing but problems.

So I implore people to think, consider and be smart and wise and understand what you're doing before you get into it. Don't just go into something, think, and glory, glory, glory. And I'm going to get this and this without a full blown understanding. And you doing the diligence to understand what you're doing

with an understanding of how to do it properly, making sure you're doing it in the safest possible manner.

I am not here to scare you.

I am not your dad. I'm not telling you what to do and how to do it.

I am giving you straight facts on what I observe

and because of what I see and what I observe, what I learn and what I'm in the trenches doing. My goal is simple. I work for God. I work for nobody else.

It is to save your life and save you from trouble and to help you live longer for your loved ones and the people that meet you. And I'm not just talking about family. Every single person has a purpose that God gave them

and that purpose needs to be fulfilled or it is a sin. And if you are unhealthy and don't take care of yourself, you cannot fulfill that purpose and I am trying to save you from that as well. That is my care, that is my goal.

And that is why I hope you listen to me and follow me. So understand what you're getting into beforehand. This is not a scare tactic. And this is not me telling you not to use them. This is me helping you understand.

Different aspects that people don't look at and then the ones that they do with the deeper explanation. So that's the talk for the day. I hope that helps. I hope it resonates and I hope you understand

where I am coming from for you. That being said, stay tuned for Plain Mortacom, Dylan Jamelli. Sign in off. (upbeat music) (upbeat music)

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