This Podcast Will Kill You
Exactly Right and iHeartPodcasts
This podcast might not actually kill you, but Erin Welsh and Erin Allmann Updyke cover so many things that can. In each episode, they tackle a different topic, teaching listeners about the biology, history, and epidemiology of a different disease or medical mystery. They do the scientific research, so you don’t have to. Since 2017, Erin and Erin have explored chronic and infectious diseases, medications, poisons, viruses, bacteria and scientific discoveries. They’ve researched public health subjects including plague, Zika, COVID-19, lupus, asbestos, endometriosis and more. Each episode is accompanied by a creative quarantini cocktail recipe and a non-alcoholic placeborita. Erin Welsh, Ph.D. is a co-host of the This Podcast Will Kill You. She is a disease ecologist and epidemiologist and works full-time as a science communicator through her work on the podcast. Erin Allmann Updyke, MD, Ph.D. is a co-host of This Podcast Will Kill You. She’s an epidemiologist and disease ecologist currently in the final stretch of her family medicine residency program. This Podcast Will Kill You is part of the Exactly Right podcast network that provides a platform for bold, creative voices to bring to life provocative, entertaining and relatable stories for audiences everywhere. The Exactly Right roster of podcasts covers a variety of topics including science, true crime, comedic interviews, news, pop culture and more. Podcasts on the network include My Favorite Murder with Karen Kilgariff and Georgia Hardstark, Buried Bones, That's Messed Up: An SVU Podcast and more.
Recent Episodes
20 episodesEp 202 Cancer Part 1: What is it?
Cancer has touched every one of us in some capacity, and learning of a diagnosis inspires many more questions than it answers. In this four-part series on cancer, we aim to lay a foundation of knowledge that will help make sense of this multifaceted disease. We begin our four-part series on cancer by asking a deceptively simple question: what is cancer? As we’ll discover over the course of these episodes, there is not one answer but many. After all, cancer is not one disease but many. In this first episode, we examine the clinical definitions of cancer - when someone receives a cancer diagnosis, how is that determined, and what does that mean? Viewing that question through a historical lens reveals our changing understanding of cancer and how that knowledge filters into the public perception of this disease. With cancer diagnoses on the rise, it’s tempting to label cancer a disease of the 20th or 21st centuries. But is that the case? Tune in to find out. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.
Special Episode: Jon Adams and Edmund Ramsden & Rat City
What happens if you put a bunch of rats in an enclosure and provision them with unlimited food and water? Researcher John B. Calhoun was committed to finding out. Results from Calhoun’s “rat utopia” experiments from the mid-20th century revealed a behavioral dark side that emerged as space grew increasingly limited, ultimately leading to complete population collapse. As headlines conveyed dire warnings about global overpopulation, Calhoun’s work served to reinforce those fears and shape our understanding of the importance of personal space. In this week’s TPWKY book club episode, Jon Adams and Edmund Ramsden join me to discuss their book, Rat City: Overcrowding and Urban Derangement in the Rodent Universes of John B. Calhoun. Tune in for a fascinating a tour through Calhoun’s bizarre and influential research, which even inspired a beloved (if a little creepy) children’s book and movie, Mrs. Frisby and the Rats of NIMH. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.
Ep 201 Poop Part 2: Flushed away
Poop is an incredibly valuable and massively underutilized resource. However, most of us don’t see it that way because of our evolutionarily ingrained disgust towards poop. Flush toilets and intricate sewer systems have revolutionized health and hygiene by whisking our poop far away where we don’t have to think about it. But that poop has gotta go somewhere, and eventually, not thinking about it isn’t going to be an option. Similarly, not thinking about our individual poop is asking for disaster, since what we produce can reveal a great deal about our gut and overall health. In this episode, we explore the problems that poop can cause on both the individual and population level. From constipation to fiber, and the Great Stink to communal poop sponges, we’re continuing our journey into the curiously fascinating world of poop. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.
Ep 200 Poop Part 1: How the sausage gets made
It might be stinky and it might be unpleasant to behold, but we all do it. For many of us, our poop is out of sight, out of mind once we flush it away. But for the next hour and fifteen minutes or so, we’re going to bring it back into mind as we delve into the rich world of poop. This episode, the first of a two-part miniseries on poop, features a wide cast of characters all with some role in the production or management of poo, like our intestinal tract with its sphincters and microbiota, dung beetles that perform the duties so crucial for ecosystem function, and the sperm whale that produces a revered substance used in perfumes. We’re going behind the scenes to understand how the sausage really gets made (in a manner of speaking) and why we need a big perspective shift to stop seeing poop as waste and start seeing it as a resource. Correction: EW says that elephants poop 15 pounds a day, but in reality it’s more like 10x that - 150-200 pounds! Sorry for the mistake - we noticed it while listening through. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.
Special Episode: Nicola Twilley & Frostbite
For much of the world, refrigeration is such a commonplace technology that we rarely stop to wonder at the many ways it has transformed our lives. From the foods we grow to where we grow them, from how they taste to what we eat, refrigeration has dramatically - and quite recently - changed our relationship to food, our health, and the environment. As Nicola Twilley describes in Frostbite: How Refrigeration Changed our Food, Our Planet, and Ourselves, progress, as it so often does, comes at a cost. Twilley, who also cohosts the award-winning food podcast Gastropod, joins us in this week’s TPWKY book club episode to discuss the surprising history and tenuous future of refrigeration. You’ll never look at your fridge the same way again. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.
Ep 199 Sleep Part 2: Predictably unpredictable
Now that we know just how critical sleep is, we’re all making sure we get the amount we need, right? Unfortunately no. One-third to one-half of Americans are not getting enough sleep, according to public health guidelines. Why is that? Hypotheses abound, but many point the finger of blame at different aspects of modern society such as screen time, artificial light, a sedentary lifestyle. These narratives suggest that sleep in industrialized societies today is not just different but worse than in centuries past. Is that the truth? How did humans sleep in yesteryear, and what can that tell us about sleep today? In the conclusion to our sleep two-parter, we explore the many ways that humans sleep and the wide array of consequences when we don’t get enough (or too much) of it. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.
Ep 198 Sleep Part 1: Sleeping with one eye open
Sleep is a universal experience. It’s not just the lion that sleeps tonight - it’s also the butterfly, the chicken, the jellyfish, the dog, the snake, the worm, and of course the human. What is this widespread physiological process whose spell we are all under? What purpose (or purposes) does it serve? Why do we sleep the way we do? These are just some of the questions we’re going to get into in this week’s episode, the first half of our two-parter on sleep. We break down the different components of sleep in humans before diving deep into how animals sleep and what drives the different patterns we see. Night owl or daybird? Light sleeper or deep slumberer? Frequent naps or one big chunk? One eye open or both eyes closed? Tune in as we unravel some of the mysteries of sleep. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.
Special Episode: Daniel Stone & American Poison
The widespread use of leaded gasoline in the 20th century led to one of the world’s biggest public health and environmental disasters, the effects of which are still present today. Since its development in the 1920s, leaded gasoline has been linked to premature death, cognitive impairment, and behavioral issues in millions around the globe. How was such a toxic substance permitted to be sold, despite the tireless efforts of industrial medicine warriors like Alice Hamilton? In American Poison: A Deadly Invention and the Woman Who Battled for Environmental Justice, award-winning author and historian Daniel Stone tells the story of leaded gasoline - its heroes, its villains, and the lessons we can learn. What will emerge as this generation’s leaded gasoline? PFAS? Microplastics? Something else entirely? History doesn’t have to repeat, but it will unless we heed the lessons of the past. Tune in for a fascinating episode! Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.
Ep 197 Detox: Enemas for everyone
Ah, the new year. After the last month and a half of indulgent food and drink, disrupted schedules, and laying around the house, who doesn’t feel like they’re in need of a whole-body cleanse? There are plenty of companies who are more than happy to provide that product or service that promises to flush away toxins from your skin, gut, blood, brain, you name it. But what exactly are they selling you? In this episode, we explore the deep roots of the ever-expanding detox industry and the concept behind its billions of dollars in revenue: detoxification. What does detoxification even mean? Is there any truth to the claims that a certain diet or superfood or supplement or colonic or drink or enema or chelation therapy can “detoxify” you? Tune in to find out how many synonyms for scam we can come up with. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.
From the Vault - Endometriosis: Menstrual Backwash (Ep 88)
This episode originally aired on January 11th, 2022. Chances are you know someone with endometriosis, or perhaps you’re affected yourself. But despite its incredibly high prevalence, endo remains almost criminally understudied, undertreated, and underacknowledged. In this episode, we aim to shed light on many aspects of endometriosis, first by examining the “what” and “how” of this disease: what’s actually going on inside your body with endometriosis and how does it cause the symptoms that it does? Then we turn our sights to the why, exploring not only the possible evolutionary origins of this disease but also the deep historical roots contributing to the struggle many people still face today in obtaining a diagnosis. We discuss how although hysteria is no longer a valid medical diagnosis, it has left its mark on medicine in the form of implicit bias that leaves many people feeling unlistened to and unbelieved. We then wrap up the episode with a look at endometriosis by the numbers and some current research that leaves us feeling slightly more hopeful about the growing awareness of this disease and the need for effective treatments. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.
From the Vault - Hepatitis B: Hepatiti, Take 2 (Ep 89)
This episode originally aired on January 25th, 2022. In light of the recent changes by RFK jr’s Advisory Committee on Immunization Practices (ACIP) to eliminate the universal birth dose of the hepatitis B vaccine in the US, a decision which will result in preventable infections and deaths in this country every year, it seems timely to remind everyone of the global consequences of this incredibly prevalent pathogen. This week, we’re dipping a toe back into the vast waters of hepatitis viruses, this time with a focus on hepatitis B. The hepatitis B virus, though second to be named, was first to be discovered, and effective vaccines and treatments have been available for decades. Yet the global prevalence of this virus remains staggering, with nearly 300 million people chronically infected and 1.5 million new infections annually. So what’s going on? In this episode, we weave our way through the complicated biology of this virus and its deadly potential, the strange history of its identification that shows that you don't have to be looking for something to find it, and the current status of this virus that underlines how safe, effective tools for disease prevention are only as good as our delivery infrastructure. We are also so excited to be joined by Dr. Su Wang, Medical Director for the Center for Asian Health & Viral Hepatitis Programs at the Cooperman Barnabas Medical Center and outgoing President of the World Hepatitis Alliance. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.
Ep 196 Health Myths: Fact or fiction?
Did your grandma ever warn you against going out in the cold with wet hair because “you’ll catch your death”? Or have you ever tossed a few more carrots into your shopping basket in the hope that they’ll improve your vision? There are countless health myths about how to prevent or treat disease, what food will give you superhuman powers or turn your kid into a whirlwind of energy. But is there any truth to them? Let’s find out. In this episode, we review a handful of the most popular health myths, exploring their origins and scouring them for any scrap of truth. Tune in to learn whether these myths are fact, fiction, or somewhere in between! Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.
Special Episode: Dr. Homer Venters & Outbreak Behind Bars
[Content warning: self-harm, suicide, violence] In this day and age, we are equipped with an abundance of tools and knowledge to fight the spread of disease. Yet what good does that toolkit do if we lack the resources or the will to implement it where it is needed? One area of great need is our correctional facilities, our prisons, jails, immigration detention centers, and juvenile detention centers. In these settings, communicable disease is often allowed to spread unchecked, leading to high rates of morbidity and mortality. Meaningful change is needed, but what might that look like? In this week’s TPWKY book club episode, Dr. Homer Venters joins us to discuss his latest work, Outbreak Behind Bars: Spider Bites, Human Rights, and the Unseen Danger to Public Health. As the former Chief Medical Officer of the New York City jail system and through his current role as a federal monitor of health services in several jail and prison settings, Dr. Venters has extensive firsthand knowledge of the barriers that prevent adequate medical care to be delivered to these populations. And he has evidence-based solutions. Tune in for a necessary discussion of this humanitarian crisis. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.
Ep 195 Salt Part 2: The Substance
We ended last week’s episode on a bit of a cliffhanger: is salt actually bad for us and if so, why does there still seem to be a debate? This week’s episode holds all the answers. We’re sifting through the noise to figure out what salt actually does in our bodies, how it might impact our health, and why we crave this delicious substance. If you’ve ever wondered how we’ve arrived at the maximum daily sodium intake (2300 mg for adults) and why salt impacts blood pressure, then this is the episode for you! Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.
Ep 194 Salt Part 1: The Seasoning
Have you ever thrown a pinch of spilled salt over your left shoulder? Or said to someone “well, take his opinion with a grain of salt”? Or looked up the potential salary of a job listing? Salt is so deeply embedded in our cultures, our languages, our history as a species that we often take its influence for granted. We may forget (or perhaps we never knew) how much history is held within the unassuming yet ubiquitous salt shaker. In the first installment of this two-parter on everyone’s favorite seasoning, we delve deep into some salt lore. When did humans start to ramp up their salt intake? Why was salt such a big deal? Which places are named for salt? When did we start worrying about how much sodium we were eating? Tune in for a fun, fact-filled episode that’ll forever change the way you think about salt. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.
Special Episode: Gabriel Weston & Alive
In an anatomy and physiology class, you may learn how the different heart valves work to circulate your blood, how the structure of your kidney helps to maintain electrolyte levels, and how the expansion and contraction of your lungs sets off a carefully orchestrated cascade of gas exchange and transport. The human body is an endlessly fascinating machine. But when you spend so much time learning about the body, you can lose sight of the fact that it isn’t a machine. It is the story of your life. In this book club installment, I am joined by surgeon and award-winning writer Gabriel Weston to discuss her latest book Alive: Our Bodies and the Richness and Brevity of Existence. In this compelling blend of memoir, science, and meditation, Weston examines different body parts chapter by chapter - what they have meant to her or her loved ones, their significance in history, and how their meanings are shaped by our scientific understanding. Weston inspires readers to take a moment to reflect on what it’s like to live in your body, feel your heart beat, your lungs expand. Doing so can help us connect with ourselves and others. Tune in for a delightful conversation! Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.
Ep 193 Necrotizing Fasciitis: A strange beast
If you were asked to describe necrotizing fasciitis in three words, you might choose: rapid, deadly, and rare. The third of those adjectives may provide some comfort, but the first two are the clear inspiration for this infection’s more lurid nickname: flesh-eating bacteria. In this episode, we get up close and personal with necrotizing fasciitis and its causative agents. We start off by examining step by step how these infections wreak so much havoc and why doctors still struggle with its treatment. Then we take a tour through its grisly history, featuring maritime misadventures and wicked war wounds. We wrap up the story with a look at the global trends in these infections as well as some promising new research. This episode may not be for the faint of heart, but it is for the endlessly curious. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.
Ep 192 New World Screwworm: Oh-oh here they come
It’s the stuff nightmares are made of. A fly lands on an open wound and lays hundreds of eggs, from which hatch countless ravenous maggots. There they writhe, devouring flesh, insatiable and relentless. Every minute they dig deeper and deeper until flesh gives way to bone. Even the species name of these maggots inspires a shiver of fear: Cochliomyia hominivorax - “man eater”. This nightmare of a fly is the horrifying reality for many mammals in South America and some Caribbean islands, particularly cattle. And it seems to be making a comeback in the places it was previously eradicated - Central and North America. What exactly this fly does, why it’s such a problem, and how we came to defeat it (temporarily) all feature in this week’s episode. Sterile flies? Archival footage? Gnarly descriptions? This episode has it all. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.
Special Episode: Dr. Lindsey Fitzharris and Adrian Teal & Dead Ends!
Science doesn’t always get it right the first time (or the second, or the third, or even the ninety-ninth!). And while we may chuckle at the outlandish things people believed or the goofy experiments they tried, we forget two things: 1) those failures helped us get where we are today and 2) a hundred years from now, people will probably be laughing at the “cutting edge” medical knowledge of today! In this week’s book club episode, Erin and I chat with two of our all-time favorite science communicators, Dr. Lindsey Fithzarris and Adrian Teal to discuss their newest book Dead Ends!: Flukes, Flops & Failures That Sparked Medical Marvels. This hilarious and insightful book, geared towards middle-school readers (but enjoyable for all ages!), frolicks through some of the strangest stories in the history of medicine, accompanied by delightfully grotesque illustrations. There’s learning, there’s laughter, but most importantly, there’s a lesson: failure is okay. Not just okay but a necessary part of science. Tune in for all this and more! Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.
Ep 191 Famine: More than starvation
As we learned last week, starvation extends far beyond hunger and what a lack of food does to the human body. Similarly, famine is much more than a food shortage and starvation on a population-level scale. This week, we’re picking up where we left off last episode to explore the definitions, drivers, and many dimensions of famine. We trace famines throughout human history, asking how they have changed either in their incidence, severity, or cause. No two famines are exactly alike, but taking a bird’s eye view of patterns in famine over time gives us insight, especially into the famines of the past 100 years. We conclude the episode with a discussion of the ongoing famine in Gaza and other food insecurity crises in other regions of the world. Tune in for a broad overview of this heavy but incredibly important topic. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.