The Dylan Gemelli Podcast
The Dylan Gemelli Podcast

Episode #104 Better than BPC-157? Let's talk about KPV! The major benefits of KPV, gut health, fighting inflammation, skin and wound healing, immune function support, synergy with BPC-157 and more!!

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Episode #104 Better than BPC-157?  Let's talk about KPV!!   In this episode we take a look at one of my favorite peptides, KPV.  Get ready for a breakdown on the multitude of benefits KPV has to offer...

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save $90 with my special discount. Take control over your health today with a Palo Neuro. Now listen to this. It actually downregulates oxidative stress pathways. I believe it is stronger. It does more. This is like the next generation BPC that everybody's going to be wanting to use it.

I will never, ever put doubt on that. Better than BPC 157? Really? Is that possible?

Something that is going to be more popular and more widely used? Oh, I don't know because everybody under the sun wants to talk about BPC 157 and rightfully so because it is tremendous, but there are other compounds out there that do some amazing things. And I'm going to talk to you about what I believe is the most underrated peptide in existence. It is at the top of my list of new favorites. And that is KPV. Now I am Dylan Jamilly. I am your resident expert when it comes to

hormones peptides and biohacking in general. And I listen, I am only smart because I hang around smart people and I just have years of experience and study and a lot of onhand coaching, seeing how things work. And I have learned from some of the best people around the world, especially when it comes to peptides. So I am going to get into some things here talking about KPV. Now most people have kind of learned about KPV through the CLOW stack because at first it was the

glow stack, which we know is BPC 157, TB500, and GHKCU copper peptide. But then we started to see

the CLOW stack. And I believe it was called CLOW because we added the KPV to it. I think that is the

shining star. I will not come out here and say that it is better than BPC 157. But it is extremely synergistic with it because look, BPC is a phenomenal. It is body protective compound. It is one of the most well known, most reputable, if not the most reputable peptide and most popular and

existence and rightfully so I will never, ever put doubt on that. However, KPV works synergistically

with it extremely well. So what I am going to do is give you an explanation here on KPV. What it is, what it does, why I love it so much. And then we are going to talk about the synergy between the two. So it is a tri peptide of three amino acids. So we are talking about lysine, proline, and valine. Now it is a fragment of a larger molecule. And that is known as a MSH. And that plays a central role in immune function, inflammation control, and a melanogenesis. One of the things

that makes KPV a standout and really unique is that it retains all the anti-inflammatory benefits of an AMSH without stimulating melanocyte receptors. So that makes it really safe for systemic use without affecting pigmentation or hormone levels in any way shape or form. Now I am going to run down some of the benefits of KPV. Number one is that it has really, really strong anti-inflammatory effects. Now it has been shown to suppress pro-inflammatory cytokines, which are implicated

in numerous chronic conditions. And this makes it really valuable in controlling systemic and localized inflammation without suppressing the immune system entirely like steroids would.

Number two, and this is one of the things that I think it's most well known for and one of the

things that I absolutely love about it. It supports gut healing as well as barrier function. So one of the most exciting aspects of KPV's application is in healing the intestinal, mucosal barrier. Now it enhances epithelial cell regeneration and it reduces inflammatory signaling.

It promotes tight junction integrity and this is crucial for yes, addressing leaky gut syndrome

Other food sensitivities, IBD, etc.

activity. Rather than suppressing immunity, KPV modulates it. So it helps calm an overactive immune

response without compromising defense mechanisms. It makes it really ideal for autoimmune diseases, histamine intolerance, mast cell activation syndrome also known as MCAS gastrointestinal disorders. So it does a ton. What else does it do? It improves skin conditions. It has topical and systemic applications in improving psoriasis, exima inflammatory acne. Then these effects are due to its

suppression of inflammatory mediators as well as restoration of skin barrier function. What else?

It protects against oxidative stress. Now listen to this. It actually downregulates oxidative

stress pathways and reduces reactive oxygen species and what does that do? It gives protection

at the cellular level and it improves tissue healing, especially in the gut, the brain and our skin. Here's one of my favorite aspects aside from the gut health that we talked about. It supports neurological health. You guys have heard me talk a ton now recently about the mind body connection you know about my studies in neuroscience. So what does it do? It reduces neuro inflammation and oxidative stress. So we're talking about helping with brain fog, migraines, neuro degenerative

concerns, mood disorders that are tied to inflammation. Now let's talk about mechanism of action.

Here, how does it work? It works by targeting several different pathways simultaneously.

I'm going to throw some stuff out here at you. So in inhibits NFKB activation and that is a central

pro inflammatory transcription factor. Now it suppresses IL6 TNFA and MCP1. These are common inflammatory cytokines and it also restores tight junction proteins which then reduces gut permeability. It also calms mass cells and modulating allergic and autoimmune responses and it downregulates TLR4 which reduces in a immune over activation and it's safety and systemic tolerance make it a very unique versatile peptide in the anti-inflammatory toolkit. It's often described as an anti-inflammatory

peptide as you can see, but inflammation is only one piece of recovery reducing inflammation helps, but healing. This depends on tissue signaling circulation and repair capacity. The injury joint and recovery blueprint explains where peptides like KPV fit and why controlling inflammation and known isn't enough. You got to get the joint and injury recovery blueprint and read that and learn about it. Now who should consider KPV peptide therapy? It's ideal for people that have gastrointestinal

issues, inflammation, Crohn's ulcerative colitis, IVS, leaky gut, esophagitis, post-antibiotic gut, dyspiosis, autoimmune and inflammatory conditions, psoriasis, rheumatoid arthritis, Hashimoto's, Lupus, histamine intolerance, MCAS. I mean, there's a long list of things. It helps stabilize mass cells like I said, reduce histamine, mediated symptoms and restore gut-lining integrity. Skin conditions like I talked about acne, Xima, chronic dermatitis and it also accelerates

tissue healing and it dampens post trauma inflammation, particularly in soft tissues and mucosolines. BPC-157 is largely focused on tissue repair and regeneration while KPV is a specialized anti-inflammatory and immune-modulating peptide. So they're often used together to create a very comprehensive healing protocol that addresses both physical injury and inflammation. So just real quick to touch on BPC-157. BPC-157 works by increasing angiogenesis, which is new blood vessel growth. It improves circulation

to our injured areas and accelerates cell regeneration. So it's best for injuries like our tendon ligaments, muscles, post-surgical recovery, chronic gut issues like ulcers and joint pain. And it's known for his ability to promote healing, even in harsh environments like the digestive

tract. Now I covered everything there is to know about KPV. What are we going to do here with these?

Are we going to stack them? Are we going to use them separately? You can use them separately just fine. I assure you they do extremely well on their own. But when they use together, they offer a very synergistic approach to healing, comprehensive gut health because BPC repairs the structural damage while KPV reduces the inflammation that caused the damage. Then let's look at some advanced recovery. So BPC accelerates tissue repair and KPV manages

The inflammatory response so that reduces the overall recovery time.

and jelly. And that's one of the things I love is that while used on their own, some of these are

absolutely phenomenal. But when you start stacking them together and you see the synergy and you see

how they work hand in hand, it is on an entirely different level. So KPV to me, it is the most

underrated peptide right now. But more and more people are starting to get up to speed on it and

understand. To me, this is like the next generation BPC that everybody's going to be wanting to use it, especially with all of the understanding it could certainly on leaky gut and all of these other

conditions that I talked about. And I truly believe that I know that everybody uses BPC and TB500

as like their master stack. I think KPV will replace TB500. I believe it is stronger. It does more TB500 works extremely well with BPC 157. No doubt there's no doubt there's whatsoever. I've been a huge performer of that. But if you had to pick between all four and the close stack

and as much as I love GHKCU, the first two I would pick would be BPC 157 and KPV all day long.

That's the synopsis there. Is it better than BPC 157? That's arguable. Considering that it addresses something that is so preble of a problem and we're talking about leaky gut,

I believe that is one of the biggest problems and biggest culprits and the degradation of

overall health and as much as necessary as BPC is for injury, healing and prevention, I think leaky gut is a much bigger problem. I think there's a fair argument there in KPD's favor, but to each their own. I'm only here to give facts. So that being said, stay tuned for play and work calm, Dylan Jamelli. Sign it off.

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